ABSTRACT
Objective To analyze the tendency of road traffic injuries and explore its main influencing factors in China from 1997 to 2016, so as to provide references for decision-making of prevention and control. Methods Data was collected from national data website. Annual percent change (APC) and average annual percent change (AAPC) were calculated and trend tests were performed by Joinpoint Regression Program 4.6.0.0. Results The overall trend of the indexes was basically the same, reaching the highest record in 2002. The following downward tendency was different and tended to level off after 2009. However, the forecast showed that the fatality of road traffic accidents would increase slightly in recent years. For different road traffic modes, only the average annual percent change of motor vehicle injuries statistically descended (AAPC=-1.83, Z=-2.23, P=0.026). The average annual decreases of non-motor vehicle deaths were statistically significant (AAPC=-1.98, Z=-2.47, P=0.014), and the number of injured showed a notable upward trend instead (AAPC=3.95, Z=5.16, P<0.001). The indexes of walking and riding were declined markedly (AAPC≥7.90, P<0.001). Conclusions The status of walking and riding had been improved significantly, but motor vehicles injuries were still the main traffic mode causing road traffic injuries. The safety situation of non-motor vehicles was increasingly serious. Adopting legal compulsory measures and other intervention to routine systematic management was quite necessary.
ABSTRACT
The aim of this study was to examine the associations between depression and inflammatory markers in patients admitted to the hospital for myocardial infarction. Inflammatory cytokines, including high-sensitivity C-reactive protein [hs-CRP], interleukin [IL]-1beta, IL-6, and tumor necrosis factor-alpha [TNF-alpha] were assessed in a group of 75 depressed participants [score of >/= 12] and compared to a control group of 75 nondepressed participants [score < 12], all who had been admitted to the hospital for myocardial infarction. The presence of depressive symptoms was assessed using the Beck Depressive Symptoms Inventory II Scale [BDI-II]. Depressed myocardial infarction participants had significantly greater levels of TNF-alpha [t = 2.070, P < 0.05] compared with control myocardial infarction participants. The BDI-II score was positively correlated with TNF-alpha levels [r = 0.222, P < 0.05]. These results indicate that the presence of depressive symptoms is positively associated with TNF-alpha levels among patients who have suffered from myocardial infarction